Where we live and where our ancestors lived depends on access to clean water. This finite resource supports all life, including over 7 billion people today. As we use this water to live, it continues it path through the water cycle either evaporating or following a path of least resistance down hill. When water leaves us, where does it go, and what are the impacts? If we look globally at the surface drainage, we can see the basins which drain the great river systems of the world. These rivers are the single largest renewable water resource for humans and are in crisis, suffering the impact of pollution, dam building, agricultural runoff, the conversion of wetlands and the introduction of exotic species. Nearly 80 percent of the world's human population lives in areas where river waters are highly threatened posing a major threat to human water security and resulting in aquatic environments where thousands of species of plants and animals are at risk of extinction. This impact is perhaps most pronounced, where these great rivers enter the ocean. In every case, they are marked by Dead Zones, Areas of low oxygen (hypoxic).Chemical nutrients carried down river (particularly nitrogen and phosphorus) cause a rapid explosion in the growth of phytoplankton based algal blooms, consuming the available oxygen in the water. This process known as Eutrophication, can be caused by natural and by anthropogenic factors. We all live somewhere along the water cycle path. Access to this precious gift carries both rights and a responsibilities.